Computationally repurposed drugs and natural products against RNA dependent RNA polymerase as potential COVID-19 therapies

Abstract Repurposing of existing drugs and drug candidates is an ideal approach to identify new potential therapies for SARS-CoV-2 that can be tested without delay in human trials of infected patients. Here we applied a virtual screening approach using Autodock Vina and molecular dynamics simulation...

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Bibliographic Details
Main Authors: Sakshi Piplani, Puneet Kumar Singh, David A. Winkler, Nikolai Petrovsky
Format: Article
Language:English
Published: Springer 2021-09-01
Series:Molecular Biomedicine
Subjects:
Online Access:https://doi.org/10.1186/s43556-021-00050-3