Resolving Genotype–Phenotype Discrepancies of the Kidd Blood Group System Using Long-Read Nanopore Sequencing

Resolving Genotype–Phenotype Discrepancies of the Kidd Blood Group System Using Long-Read Nanopore Sequencing

Due to substantial improvements in read accuracy, third-generation long-read sequencing holds great potential in blood group diagnostics, particularly in cases where traditional genotyping or sequencing techniques, primarily targeting exons, fail to explain serological phenotypes. In this study, we...

Full description

Bibliographic Details
Main Authors: Morgan Gueuning, Gian Andri Thun, Nadine Trost, Linda Schneider, Sonja Sigurdardottir, Charlotte Engström, Naemi Larbes, Yvonne Merki, Beat M. Frey, Christoph Gassner, Stefan Meyer, Maja P. Mattle-Greminger
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biomedicines
Subjects:
Kidd blood group system
structural variant
Oxford nanopore sequencing
haplotype
long-read sequencing
high-throughput genotyping
Online Access:https://www.mdpi.com/2227-9059/12/1/225

Internet

https://www.mdpi.com/2227-9059/12/1/225

Similar Items