mIgM-mediated splenic marginal zone B cells targeting of folic acid for immunological evasion

mIgM-mediated splenic marginal zone B cells targeting of folic acid for immunological evasion

Folic acid is a fully oxidized synthetic folate with high bioavailability and stability which has been extensively prescribed to prevent congenital disabilities. Here we revealed the immunosuppressive effect of folic acid by targeting splenic marginal zone B (MZB) cells. Folic acid demonstrates avid...

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Bibliographic Details
Main Authors: Huan Wang, Zhuxuan Jiang, Zhiwei Guo, Gan Luo, Tianhao Ding, Changyou Zhan
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Membrane-bound IgM
Anti-drug antibodies
B cell anergy
Folic acid
Marginal zone B cells
B cell receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383523003647

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http://www.sciencedirect.com/science/article/pii/S2211383523003647

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