3177 Determining mechanisms underlying hippocampal network disruption in early amyloid pathology

OBJECTIVES/SPECIFIC AIMS: Alzheimer’s disease (AD) is the leading cause of dementia, and a rapidly growing public health crisis as life expectancy increases. Two hallmark symptoms of the disease are memory impairment and the pathological accumulation of amyloid beta protein. The hippocampus is a bra...

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Bibliographic Details
Main Authors: Adam Caccavano, P. Lorenzo Bozzelli, Katherine Conant, Stefano Vicini
Format: Article
Language:English
Published: Cambridge University Press 2019-03-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S205986611900236X/type/journal_article