The KASH5 protein involved in meiotic chromosomal movements is a novel dynein activating adaptor

The KASH5 protein involved in meiotic chromosomal movements is a novel dynein activating adaptor

Dynein harnesses ATP hydrolysis to move cargo on microtubules in multiple biological contexts. Dynein meets a unique challenge in meiosis by moving chromosomes tethered to the nuclear envelope to facilitate homolog pairing essential for gametogenesis. Though processive dynein motility requires bindi...

Full description

Bibliographic Details
Main Authors: Ritvija Agrawal, John P Gillies, Juliana L Zang, Jingjing Zhang, Sharon R Garrott, Hiroki Shibuya, Jayakrishnan Nandakumar, Morgan E DeSantis
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-06-01
Series:eLife
Subjects:
microtubules
cytoplasmic dynein 1
meiosis
KASH5
EF-hand
LINC complex
Online Access:https://elifesciences.org/articles/78201

Internet

https://elifesciences.org/articles/78201

Similar Items