Growth differentiation factor 15 (GDF15) predicts relapse free and overall survival in unresected locally advanced non-small cell lung cancer treated with chemoradiotherapy

Growth differentiation factor 15 (GDF15) predicts relapse free and overall survival in unresected locally advanced non-small cell lung cancer treated with chemoradiotherapy

Abstract Introduction Growth differentiation factor 15 (GDF15) is a cytokine of the TGFβ family. Here, we analyzed GDF15 levels in patients with locally advanced non-small cell lung cancer (LA-NSCLC) who participated in OCOG-ALMERA (NCT02115464), a phase II randomized clinical trial, that investigat...

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Bibliographic Details
Main Authors: Fiorella Di Pastena, Gregory Pond, Evangelia E. Tsakiridis, Andre Gouveia, Elham Ahmadi, Olga-Demetra Biziotis, Amr Ali, Anand Swaminath, Gordon Okawara, Peter M. Ellis, Bassam Abdulkarim, Naseer Ahmed, Andrew Robinson, Wilson Roa, Mario Valdes, Peter Kavsak, Marcin Wierzbicki, James Wright, Gregory Steinberg, Theodoros Tsakiridis
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Radiation Oncology
Subjects:
Lung cancer biomarker
GDF15
Concurrent chemoradiotherapy
Metformin
Online Access:https://doi.org/10.1186/s13014-024-02546-y

Internet

https://doi.org/10.1186/s13014-024-02546-y

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