Self-growing protocell models in aqueous two-phase system induced by internal DNA replication reaction

Abstract The bottom-up reconstitution of self-growing artificial cells is a critical milestone toward realizing autonomy and evolvability. However, building artificial cells that exhibit self-growth coupled with internal replication of gene-encoding DNA has not been achieved yet. Here, we report sel...

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Bibliographic Details
Main Authors: Yoshihiro Minagawa, Moe Yabuta, Masayuki Su’etsugu, Hiroyuki Noji
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56172-7