Effects of pyrroloquinoline quinone on noise-induced and age-related hearing loss in mice

Abstract We investigated whether the oxidoreductase cofactor pyrroloquinoline quinone (PQQ) prevents noise-induced and age-related hearing loss (NIHL and ARHL) in mice. To assess NIHL, 8 week-old mice with and without PQQ administration were exposed to noise for 4 h. PQQ was orally administered for...

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Bibliographic Details
Main Authors: Ying Gao, Teru Kamogashira, Chisato Fujimoto, Shinichi Iwasaki, Tatsuya Yamasoba
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-19842-w