The Epigenetic Factor KDM2B Regulates EMT and Small GTPases in Colon Tumor Cells

The Epigenetic Factor KDM2B Regulates EMT and Small GTPases in Colon Tumor Cells

Background/Aims: The epigenetic factor KDM2B is a histone demethylase expressed in various tumors. Recently, we have shown that KDM2B regulates actin cytoskeleton organization, small Rho GTPases signaling, cell-cell adhesion and migration of prostate tumor cells. In the present study, we addressed i...

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Bibliographic Details
Main Authors: Nefeli Zacharopoulou, Anna Tsapara, Galatea Kallergi, Evi Schmid, Saad Alkahtani, Saud Alarifi, Philip N. Tsichlis, Sotirios C. Kampranis, Christos Stournaras
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Colon cancer
KDM2B
Small-GTPases
EMT
Online Access:https://www.karger.com/Article/FullText/489917

Internet

https://www.karger.com/Article/FullText/489917

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