Eliminating both canonical and short-patch mismatch repair in Drosophila melanogaster suggests a new meiotic recombination model.

In most meiotic systems, recombination is essential to form connections between homologs that ensure their accurate segregation from one another. Meiotic recombination is initiated by DNA double-strand breaks that are repaired using the homologous chromosome as a template. Studies of recombination i...

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Bibliographic Details
Main Authors: K Nicole Crown, Susan McMahan, Jeff Sekelsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4154643?pdf=render