Limited ability of increased sequencing depth in detecting cases missed by noninvasive prenatal testing: a comparative analysis of 3 clinical cases

Limited ability of increased sequencing depth in detecting cases missed by noninvasive prenatal testing: a comparative analysis of 3 clinical cases

Abstract Increased sequencing depth can improve the detection rate of noninvasive prenatal testing (NIPT) for chromosome aneuploidies and copy number variations (CNVs). However, due to the technical limitations of NIPT, false-positives and false-negatives are inevitable. False-positives for aneuploi...

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Bibliographic Details
Main Authors: Yinghong Lu, Na Zuo, Minxia Ning, Yuling Xie, Weiwu Liu, Sisi Ning, Yi Liang, Xiao Chen, Yuping Zhang, Jun Feng, Yunrong Qin
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-52767-0

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https://doi.org/10.1038/s41598-024-52767-0

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