Obligately aerobic human gut microbe expresses an oxygen resistant tungsten-containing oxidoreductase for detoxifying gut aldehydes

Obligately aerobic human gut microbe expresses an oxygen resistant tungsten-containing oxidoreductase for detoxifying gut aldehydes

Brevibacillus massiliensis strain phR is an obligately aerobic microbe that was isolated from human feces. Here, we show that it readily takes up tungsten (W), a metal previously associated only with anaerobes. The W is incorporated into an oxidoreductase enzyme (BmWOR) that was purified from native...

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Bibliographic Details
Main Authors: Michael P. Thorgersen, Gerrit J. Schut, Farris L. Poole, Dominik K. Haja, Saisuki Putumbaka, Harriet I. Mycroft, Willem J. de Vries, Michael W. W. Adams
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Microbiology
Subjects:
human gut microbiome
aerobe
aldehyde oxidation
benzaldehyde
tungsten
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.965625/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.965625/full

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