Nucleolar stress in Drosophila neuroblasts, a model for human ribosomopathies

Different stem cells or progenitor cells display variable threshold requirements for functional ribosomes. This is particularly true for several human ribosomopathies in which select embryonic neural crest cells or adult bone marrow stem cells, but not others, show lethality due to failures in ribos...

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Bibliographic Details
Main Authors: Sonu Shrestha Baral, Molly E. Lieux, Patrick J. DiMario
Format: Article
Language:English
Published: The Company of Biologists 2020-04-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/9/4/bio046565