Functional regulation of an ancestral RAG transposon ProtoRAG by a trans-acting factor YY1 in lancelet

Functional regulation of an ancestral RAG transposon ProtoRAG by a trans-acting factor YY1 in lancelet

Lancelet expresses an ancestral RAG transposon, ProtoRAG, which predates human RAGgenes that are responsible for V(D)J recombination and adaptive immunity repertoire generation. Here the authors show that ProtoRAG is functionally regulated by a tran s-acting factor, bbYY1, for tuning transposon acti...

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Bibliographic Details
Main Authors: Song Liu, Shaochun Yuan, Xiaoman Gao, Xin Tao, Wenjuan Yu, Xu Li, Shangwu Chen, Anlong Xu
Format: Article
Language:English
Published: Nature Portfolio 2020-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18261-7

Internet

https://doi.org/10.1038/s41467-020-18261-7

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