Emerging Roles of Phospholipase C Beta Isozymes as Potential Biomarkers in Cardiac Disorders

Emerging Roles of Phospholipase C Beta Isozymes as Potential Biomarkers in Cardiac Disorders

Phospholipase C (PLC) enzymes represent crucial participants in the plasma membrane of mammalian cells, including the cardiac sarcolemmal (SL) membrane of cardiomyocytes. They are responsible for the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P<sub>2</sub>) into 1,2-...

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Bibliographic Details
Main Authors: Antonietta Fazio, Camilla Evangelisti, Alessandra Cappellini, Sara Mongiorgi, Foteini-Dionysia Koufi, Irene Neri, Maria Vittoria Marvi, Michele Russo, Alessandra Ghigo, Lucia Manzoli, Roberta Fiume, Stefano Ratti
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
phospholipase C beta isozymes
cardiovascular system
cardiac hypertrophy
diabetic cardiomyopathy
myocardial ischemia/reperfusion injury
cardiac biomarkers
Online Access:https://www.mdpi.com/1422-0067/24/17/13096

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https://www.mdpi.com/1422-0067/24/17/13096

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