A Systematic Overview of Type II and III Toxin-Antitoxin Systems with a Focus on Druggability

Toxin-antitoxin (TA) systems are known to play various roles in physiological processes, such as gene regulation, growth arrest and survival, in bacteria exposed to environmental stress. Type II TA systems comprise natural complexes consisting of protein toxins and antitoxins. Each toxin and antitox...

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Bibliographic Details
Main Authors: Sung-Min Kang, Do-Hee Kim, Chenglong Jin, Bong-Jin Lee
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/10/12/515