Generation of self-organized autonomic ganglion organoids from fibroblasts

Summary: Neural organoids have been shown to serve as powerful tools for studying the mechanism of neural development and diseases as well as for screening drugs and developing cell-based therapeutics. Somatic cells have previously been reprogrammed into scattered autonomic ganglion (AG) neurons but...

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Bibliographic Details
Main Authors: Shuting Liu, Kangjian Xiang, Fa Yuan, Mengqing Xiang
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223003188