A randomised controlled trial investigating the clinical and cost-effectiveness of Alpha-Stim AID cranial electrotherapy stimulation (CES) in patients seeking treatment for moderate severity depression in primary care (Alpha-Stim-D Trial)

Abstract Background Major depression is the second leading cause of years lost to disability worldwide and is a leading contributor to suicide. However, first-line antidepressants are only fully effective for 33%, and only 40% of those offered psychological treatment attend for two sessions or more....

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Main Authors: Shireen Patel, Clement Boutry, Priya Patel, Michael P. Craven, Boliang Guo, Azhar Zafar, Joe Kai, David Smart, Debbie Butler, Fred Higton, Rebecca McNaughton, Paul M. Briley, Chris Griffiths, Neil Nixon, Kapil Sayal, Richard Morriss
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-022-06192-1