LFA-1 Activation in T-Cell Migration and Immunological Synapse Formation
Integrin LFA-1 plays a critical role in T-cell migration and in the formation of immunological synapses. LFA-1 functions through interacting with its ligands with differing affinities: low, intermediate, and high. Most prior research has studied how LFA-1 in the high-affinity state regulates the tra...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-04-01
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Series: | Cells |
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Online Access: | https://www.mdpi.com/2073-4409/12/8/1136 |