Activation of Young LINE-1 Elements by CRISPRa
Long interspersed element-1 (LINE-1; L1s) are mobile genetic elements that comprise nearly 20% of the human genome. L1s have been shown to have important functions in various biological processes, and their dysfunction is thought to be linked with diseases and cancers. However, the roles of the repe...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-12-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/25/1/424 |