Allyl Isothiocyanate Suppresses the Proliferation in Oral Squamous Cell Carcinoma via Mediating the KDM8/CCNA1 Axis

Allyl Isothiocyanate Suppresses the Proliferation in Oral Squamous Cell Carcinoma via Mediating the KDM8/CCNA1 Axis

The dysregulated expression of cyclin genes can lead to the uncontrolled proliferation of cancer cells. Histone demethylase Jumonji-C domain-containing protein 5 (KDM8, JMJD5) and cyclin A1 (CCNA1) are pivotal in cell cycle progression. A promising candidate for augmenting cancer treatment is Allyl...

Full description

Bibliographic Details
Main Authors: Cheng-Chih Hsieh, Cheng-Yu Yang, Bo Peng, Sien-Lin Ho, Chang-Huei Tsao, Chih-Kung Lin, Chun-Shu Lin, Gu-Jiun Lin, Heng-Yi Lin, Hung-Chi Huang, Szu-Chien Chang, Huey-Kang Sytwu, Wei-Tso Chia, Yuan-Wu Chen
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Biomedicines
Subjects:
oral cancer
allyl isothiocyanate
patient-derived tumor xenograft (PDTX)
KDM8/JMJD5
H3K36me2
CCNA1
Online Access:https://www.mdpi.com/2227-9059/11/10/2669

Internet

https://www.mdpi.com/2227-9059/11/10/2669

Similar Items