A cell junction pathology of neural stem cells leads to abnormal neurogenesis and hydrocephalus

A cell junction pathology of neural stem cells leads to abnormal neurogenesis and hydrocephalus

Most cells of the developing mammalian brain derive from the ventricular (VZ) and the subventricular (SVZ) zones. The VZ is formed by the multipotent radial glia/neural stem cells (NSCs) while the SVZ harbors the rapidly proliferative neural precursor cells (NPCs). Evidence from human and animal mod...

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Bibliographic Details
Main Authors: Esteban M Rodríguez, María M Guerra, Karin Vío, César González, Alexander Ortloff, Luis F Bátiz, Sara Rodríguez, María C Jara, Rosa I Muñoz, Eduardo Ortega, Jaime Jaque, Francisco Guerra, Deborah A Sival, Wilfred F. A. den Dunnen, Antonio J Jiménez, María D Domínguez-Pinos, José M Pérez-Fígares, James P McAllister, Conrad Johanson
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Biological Research
Subjects:
hydrocephalus
abnormal neurogenesis
neural stem cells
stem cell transplantation
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000300005

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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000300005

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