Prostate cancer cell-platelet bidirectional signaling promotes calcium mobilization, invasion and apoptotic resistance via distinct receptor-ligand pairs

Prostate cancer cell-platelet bidirectional signaling promotes calcium mobilization, invasion and apoptotic resistance via distinct receptor-ligand pairs

Abstract Platelets play a crucial role in cancer and thrombosis. However, the receptor-ligand repertoire mediating prostate cancer (PCa) cell-platelet interactions and ensuing consequences have not been fully elucidated. Microvilli emanating from the plasma membrane of PCa cell lines (RC77 T/E, MDA...

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Bibliographic Details
Main Authors: Kaitlin Garofano, Kameron Rashid, Michael Smith, Christine Brantner, Sumanun Suwunnakorn, David Diemert, Olivia Gordon, Anelia Horvath, Sikandar Khan, Anastas Popratiloff, Johng Rhim, Alfateh Sidahmed, Sanjay B. Maggirwar, Travis J. O’Brien, Minoli A. Perera, Norman H. Lee
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-29450-x

Internet

https://doi.org/10.1038/s41598-023-29450-x

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