Breaking the ritual metabolic cycle in order to save acetyl CoA: A potential role for mitochondrial humanin in T2 bladder cancer aggressiveness

Breaking the ritual metabolic cycle in order to save acetyl CoA: A potential role for mitochondrial humanin in T2 bladder cancer aggressiveness

Introduction: Cancer cells may exhibit outsourcing of their high energy need in order to avoid the intrinsic mitochondrial apoptosis. Reduced mitochondrial respiration and accumulation of mitochondrial genome mutations are among metabolic transformations in this regard. Mitochondrial humanin (MT-RNR...

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Bibliographic Details
Main Authors: Nesreen Nabil Omar, Reham Fathy Tash, Youssef Shoukry, Karim Omar ElSaeed
Format: Article
Language:English
Published: SpringerOpen 2017-06-01
Series:Journal of the Egyptian National Cancer Institute
Subjects:
T2 bladder cancer
Aerobic glycolysis
Mitochondrial respiration
MT-RNR2
MPC1
Online Access:http://www.sciencedirect.com/science/article/pii/S1110036217300286

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http://www.sciencedirect.com/science/article/pii/S1110036217300286

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