High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders

Abstract Multiple cancer types have limited targeted therapeutic options, in part due to incomplete understanding of the molecular processes underlying tumorigenesis and significant intra- and inter-tumor heterogeneity. Identification of novel molecular biomarkers stratifying cancer patients with di...

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Bibliographic Details
Main Authors: Garik V. Mkrtchyan, Alexander Veviorskiy, Evgeny Izumchenko, Anastasia Shneyderman, Frank W. Pun, Ivan V. Ozerov, Alex Aliper, Alex Zhavoronkov, Morten Scheibye-Knudsen
Format: Article
Language:English
Published: Nature Publishing Group 2022-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05437-w