Cumulative Epigenetic Abnormalities in Host Genes with Viral and Microbial Infection during Initiation and Progression of Malignant Lymphoma/Leukemia

Although cancers have been thought to be predominantly driven by acquired genetic changes, it is becoming clear that microenvironment-mediated epigenetic alterations play important roles. Aberrant promoter hypermethylation is a prevalent phenomenon in human cancers as well as malignant lymphoma/leuk...

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Bibliographic Details
Main Authors: Atae Utsunomiya, Tadashi Yoshino, Hiaki Sato, Mamoru Ouchida, Takashi Oka
Format: Article
Language:English
Published: MDPI AG 2011-02-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/3/1/568/