Mucosal delivery of anti-inflammatory IL-1Ra by sporulating recombinant bacteria

<p>Abstract</p> <p>Background</p> <p>Mucosal delivery of therapeutic protein drugs or vaccines is actively investigated, in order to improve bioavailability and avoid side effects associated with systemic administration. Orally administered bacteria, engineered to produ...

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Bibliographic Details
Main Authors: Ruggiero Paolo, Bossù Paola, Porzio Stefano, Boraschi Diana, Tagliabue Aldo
Format: Article
Language:English
Published: BMC 2004-10-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/4/27