Investigating CpG islands methylation in P16/Ink4 gene promoter regions and the effect of Interleukin-17 gene polymorphism on this methylation in patients with breast cancer
Background & objective: Studies have shown that increased methylation of CpG islands is one of the important mechanisms in gene silencing. Protein P16 / Ink4 plays an important role in the negative regulator of cell cycle process. Inflammation, including factors that affect gene methylation and...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Fasa University of Medical Sciences
2018-04-01
|
| Series: | Journal of Advanced Biomedical Sciences |
| Subjects: | |
| Online Access: | http://jabs.fums.ac.ir/article-1-1405-en.pdf |