Effects of Mineralocorticoid Receptor Blockade and Statins on Kidney Injury Marker 1 (KIM-1) in Female Rats Receiving L-NAME and Angiotensin II

Effects of Mineralocorticoid Receptor Blockade and Statins on Kidney Injury Marker 1 (KIM-1) in Female Rats Receiving L-NAME and Angiotensin II

Kidney injury molecule-1 (KIM-1) is a biomarker of renal injury and a predictor of cardiovascular disease. Aldosterone, via activation of the mineralocorticoid receptor, is linked to cardiac and renal injury. However, the impact of mineralocorticoid receptor activation and blockade on KIM-1 is uncer...

Full description

Bibliographic Details
Main Authors: Jiayan Huang, Ezgi Caliskan Guzelce, Shadi K. Gholami, Kara L. Gawelek, Richard N. Mitchell, Luminita H. Pojoga, Jose R. Romero, Gordon H. Williams, Gail K. Adler
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
N-omega-nitro-L-arginine methyl ester (L-NAME)
angiotensin II (ANG II)
mineralocorticoid receptor (MR)
statin
simvastatin
pravastatin
Online Access:https://www.mdpi.com/1422-0067/24/7/6500

Internet

https://www.mdpi.com/1422-0067/24/7/6500

Similar Items