Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression

<p>Abstract</p> <p>Background</p> <p><it>Drosophila </it>Groucho and its human Transducin-like-Enhancer of Split orthologs (TLEs) function as transcription co-repressors within the context of Wnt signaling, a pathway with strong links to cancer. The current...

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Bibliographic Details
Main Authors: Arce Laura, Pate Kira T, Waterman Marian L
Format: Article
Language:English
Published: BMC 2009-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/159