A monoclonal antibody against p53 cross-reacts with processing bodies.

The p53 tumor suppressor protein is an important regulator of cell proliferation and apoptosis. p53 can be found in the nucleus and in the cytosol, and the subcellular location is key to control p53 function. In this work, we found that a widely used monoclonal antibody against p53, termed Pab 1801...

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Bibliographic Details
Main Authors: María Gabriela Thomas, Luciana Luchelli, Malena Pascual, Vanesa Gottifredi, Graciela Lidia Boccaccio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3349707?pdf=render