A critical role for staphylococcal nitric oxide synthase in controlling flavohemoglobin toxicity

A critical role for staphylococcal nitric oxide synthase in controlling flavohemoglobin toxicity

Most coagulase-negative staphylococcal species, including the opportunistic pathogen Staphylococcus epidermidis, struggle to maintain redox homeostasis and grow under nitrosative stress. Under these conditions, growth can only resume once nitric oxide (NO) is detoxified by the flavohemoglobin Hmp. P...

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Bibliographic Details
Main Authors: Ryan M. Singh, Sujata S. Chaudhari, Sasmita Panda, Elizabeth H. Hutfless, Cortney E. Heim, Dhananjay Shinde, Abdulelah A. Alqarzaee, Margaret Sladek, Vineet Kumar, Matthew C. Zimmerman, Paul D. Fey, Tammy Kielian, Vinai C. Thomas
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Redox Biology
Subjects:
Staphylococcus epidermidis
Bacterial nitric oxide synthase
Flavohemoglobin
Superoxide
Respiration
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723003361

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http://www.sciencedirect.com/science/article/pii/S2213231723003361

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