Case report: Safety and efficacy of synergistic treatment using selinexor and azacitidine in patients with atypical chronic myeloid leukemia with resistance to decitabine

Case report: Safety and efficacy of synergistic treatment using selinexor and azacitidine in patients with atypical chronic myeloid leukemia with resistance to decitabine

BackgroundAtypical chronic myeloid leukemia (aCML) is a BCR::ABL1 negative myelodysplastic/myeloproliferative neoplasm with poor overall survival. Some patients can be treated by allogeneic hematopoietic stem cell transplantation (allo-HSCT) from suitable donors. The effectiveness of decitabine or a...

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Bibliographic Details
Main Authors: Lu Liu, Xiaofeng Song, Wenhao Dong, Zhao Li, Dongmei Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Oncology
Subjects:
atypical chronic myeloid leukemia
selinexor
azacitidine
case report
synergism
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1353818/full

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https://www.frontiersin.org/articles/10.3389/fonc.2024.1353818/full

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