Supplementation with a Cocoa–Carob Blend, Alone or in Combination with Metformin, Attenuates Diabetic Cardiomyopathy, Cardiac Oxidative Stress and Inflammation in Zucker Diabetic Rats

Supplementation with a Cocoa–Carob Blend, Alone or in Combination with Metformin, Attenuates Diabetic Cardiomyopathy, Cardiac Oxidative Stress and Inflammation in Zucker Diabetic Rats

Diabetic cardiomyopathy (DCM) is one of the main causes of mortality among diabetic patients, with oxidative stress and inflammation major contributors to its development. Dietary flavonoids show strong antioxidant and anti-inflammatory activities, although their potential additive outcomes in combi...

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Bibliographic Details
Main Authors: Esther García-Díez, María Elvira López-Oliva, Alicia Caro-Vadillo, Francisco Pérez-Vizcaíno, Jara Pérez-Jiménez, Sonia Ramos, María Ángeles Martín
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Antioxidants
Subjects:
heart
flavonoids
diabetes
antioxidants
metformin
SIRT1
Online Access:https://www.mdpi.com/2076-3921/11/2/432

Internet

https://www.mdpi.com/2076-3921/11/2/432

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