RNA N6-methyladenosine reader IGF2BP3 interacts with MYCN and facilitates neuroblastoma cell proliferation

Abstract Neuroblastoma (NB) is a kind of typical life-threatening extracranial tumor in children. N6-methyladenosine (m6A) modification is closely related to multiple cancer pathological processes. Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) is a top-ranked prognostic risk gene in...

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Bibliographic Details
Main Authors: Kai Zhu, Tingting Gao, Zhiru Wang, Liaoran Zhang, Kezhe Tan, Zhibao Lv
Format: Article
Language:English
Published: Nature Publishing Group 2023-05-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01449-3