Dendritic Kv4.2 potassium channels selectively mediate spatial pattern separation in the dentate gyrus

Summary: The capacity to distinguish comparable experiences is fundamental for the recall of similar memories and has been proposed to require pattern separation in the dentate gyrus (DG). However, the cellular mechanisms by which mature granule cells (GCs) of the DG accomplish this function are poo...

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Bibliographic Details
Main Authors: Marie Oulé, Erika Atucha, Tenyse M. Wells, Tamar Macharadze, Magdalena M. Sauvage, Michael R. Kreutz, Jeffrey Lopez-Rojas
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221008440