Mitochondrial dysfunctions induce PANoptosis and ferroptosis in cerebral ischemia/reperfusion injury: from pathology to therapeutic potential

Mitochondrial dysfunctions induce PANoptosis and ferroptosis in cerebral ischemia/reperfusion injury: from pathology to therapeutic potential

Ischemic stroke (IS) accounts for more than 80% of the total stroke, which represents the leading cause of mortality and disability worldwide. Cerebral ischemia/reperfusion injury (CI/RI) is a cascade of pathophysiological events following the restoration of blood flow and reoxygenation, which not o...

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Bibliographic Details
Main Authors: Ruining She, Danhong Liu, Jun Liao, Guozuo Wang, Jinwen Ge, Zhigang Mei
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
ischemic stroke
cerebral ischemia/reperfusion injury (CI/RI)
mitochondrial dysfunctions
PANoptosis
PANoptosome
ferroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1191629/full

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https://www.frontiersin.org/articles/10.3389/fncel.2023.1191629/full

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