Effects of Melittin Treatment in Cholangitis and Biliary Fibrosis in a Model of Xenobiotic-Induced Cholestasis in Mice

Cholangiopathy is a chronic immune-mediated disease of the liver, which is characterized by cholangitis, ductular reaction and biliary-type hepatic fibrosis. There is no proven medical therapy that changes the course of the disease. In previous studies, melittin was known for attenuation of hepatic...

Full description

Bibliographic Details
Main Authors: Kyung-Hyun Kim, Hyun-Jung Sung, Woo-Ram Lee, Hyun-Jin An, Jung-Yeon Kim, Sok Cheon Pak, Sang-Mi Han, Kwan-Kyu Park
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/7/9/3372