Native proline-rich motifs exploit sequence context to target actin-remodeling Ena/VASP protein ENAH

Native proline-rich motifs exploit sequence context to target actin-remodeling Ena/VASP protein ENAH

The human proteome is replete with short linear motifs (SLiMs) of four to six residues that are critical for protein-protein interactions, yet the importance of the sequence surrounding such motifs is underexplored. We devised a proteomic screen to examine the influence of SLiM sequence context on p...

Full description

Bibliographic Details
Main Authors: Theresa Hwang, Sara S Parker, Samantha M Hill, Robert A Grant, Meucci W Ilunga, Venkatesh Sivaraman, Ghassan Mouneimne, Amy E Keating
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-01-01
Series:eLife
Subjects:
short linear motif
actin
ena/vasp
EVH1
protein-protein interaction
Online Access:https://elifesciences.org/articles/70680

Internet

https://elifesciences.org/articles/70680

Similar Items