Cingulate white matter mediates the effects of fecal Ruminococcus on neuropsychiatric symptoms in patients with amyloid-positive amnestic mild cognitive impairment

Cingulate white matter mediates the effects of fecal Ruminococcus on neuropsychiatric symptoms in patients with amyloid-positive amnestic mild cognitive impairment

Abstract Background Microbiota-gut-brain axis interacts with one another to regulate brain functions. However, whether the impacts of gut dysbiosis on limbic white matter (WM) tracts contribute to the neuropsychiatric symptoms (NPS) in patients with amyloid-positive amnestic mild cognitive impairmen...

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Bibliographic Details
Main Authors: Chun-Che Hung, Yi-Ping Chao, Yejin Lee, Chi-Wei Huang, Shu-Hua Huang, Chiung-Chih Chang, Chia-Hsiung Cheng
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Geriatrics
Subjects:
Amnestic mild cognitive impairment
Diffusion tensor imaging
Gut microbiota
Limbic system
Neuropsychiatric symptoms
Ruminococcus
Online Access:https://doi.org/10.1186/s12877-023-04417-9

Internet

https://doi.org/10.1186/s12877-023-04417-9

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