Intertwining threshold settings, biological data and database knowledge to optimize the selection of differentially expressed genes from microarray.

Intertwining threshold settings, biological data and database knowledge to optimize the selection of differentially expressed genes from microarray.

BACKGROUND: Many tools used to analyze microarrays in different conditions have been described. However, the integration of deregulated genes within coherent metabolic pathways is lacking. Currently no objective selection criterion based on biological functions exists to determine a threshold demons...

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Bibliographic Details
Main Authors: Paul Chuchana, Philippe Holzmuller, Frederic Vezilier, David Berthier, Isabelle Chantal, Dany Severac, Jean Loup Lemesre, Gerard Cuny, Philippe Nirdé, Bruno Bucheton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2958130?pdf=render

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http://europepmc.org/articles/PMC2958130?pdf=render

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