Combined intramuscular and intraspinal transplant of bone marrow cells improves neuromuscular function in the SOD1G93A mice

Combined intramuscular and intraspinal transplant of bone marrow cells improves neuromuscular function in the SOD1G93A mice

Abstract Background The simultaneous contribution of several etiopathogenic disturbances makes amyotrophic lateral sclerosis (ALS) a fatal and challenging disease. Here, we studied two different cell therapy protocols to protect both central and peripheral nervous system in a murine model of ALS. Me...

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Bibliographic Details
Main Authors: Anna Martínez-Muriana, Diego Pastor, Renzo Mancuso, Amaya Rando, Rosario Osta, Salvador Martínez, Rubèn López-Vales, Xavier Navarro
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Stem Cell Research & Therapy
Subjects:
ALS
SOD1
Bone marrow
Stem cells
Motoneuron disease
Online Access:https://doi.org/10.1186/s13287-020-1573-6

Internet

https://doi.org/10.1186/s13287-020-1573-6

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