Clinicopathological characteristics and loss of mismatch repair protein expression in Chinese upper tract urothelial carcinomas

Expression of DNA mismatch repair (MMR) protein (MLH1, PMS2, MSH2, and MSH6) in upper tract urothelial carcinoma (UTUC) has been explored in Western cohorts, but it is rarely reported in Eastern cohorts. We aimed to assess the loss of MMR protein expression among Chinese UTUC patients and study its...

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Bibliographic Details
Main Authors: Zhi Shang, Shengming Jin, Wenwen Wang, Yu Wei, Chengyuan Gu, Chen Yang, Yu Zhu, Yao Zhu, Yijun Shen, Junlong Wu, Dingwei Ye
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1012168/full