CE-BLAST makes it possible to compute antigenic similarity for newly emerging pathogens

Sparse immune-binding data for emerging pathogens limits the ability of existing in silico antigenicity prediction methods to aid vaccine design. Here, the authors introduce a computational method that estimates antigenic pathogen similarity based on epitope structure.

Bibliographic Details
Main Authors: Tianyi Qiu, Yiyan Yang, Jingxuan Qiu, Yang Huang, Tianlei Xu, Han Xiao, Dingfeng Wu, Qingchen Zhang, Chen Zhou, Xiaoyan Zhang, Kailin Tang, Jianqing Xu, Zhiwei Cao
Format: Article
Language:English
Published: Nature Portfolio 2018-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-04171-2