Altered vasoreactivity in neonatal rats with pulmonary hypertension associated with bronchopulmonary dysplasia: Implication of both eNOS phosphorylation and calcium signaling.

Bronchopulmonary dysplasia (BPD) consists of an arrest of pulmonary vascular and alveolar growth, with persistent hypoplasia of the pulmonary microvasculature and alveolar simplification. In 25 to 40% of the cases, BPD is complicated by pulmonary hypertension (BPD-PH) that significantly increases th...

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Bibliographic Details
Main Authors: Eric Dumas de la Roque, Gwladys Smeralda, Jean-François Quignard, Véronique Freund-Michel, Arnaud Courtois, Roger Marthan, Bernard Muller, Christelle Guibert, Mathilde Dubois
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5325597?pdf=render