Prioritisation of potential drug targets against Bartonella bacilliformis by an integrative in-silico approach

Prioritisation of potential drug targets against Bartonella bacilliformis by an integrative in-silico approach

BACKGROUND Carrion’s disease (CD) is a neglected biphasic illness caused by Bartonella bacilliformis, a Gram-negative bacteria found in the Andean valleys. The spread of resistant strains underlines the need for novel antimicrobials against B. bacilliformis and related bacterial pathogens. OBJECTI...

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Bibliographic Details
Main Authors: Mariella Farfán-López, Abraham Espinoza-Culupú, Ruth García-de-la-Guarda, Federico Serral, Ezequiel Sosa, María Mercedes Palomino, Darío A Fernández Do Porto
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2020-08-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Bartonella bacilliformis
drug targets
structurome
metabolic networks
Carrion’s disease
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762020000100335&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762020000100335&tlng=en

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