Modulation of Autophagy Direction to Enhance Antitumor Effect of Endoplasmic‐Reticulum‐Targeted Therapy: Left or Right?

Abstract Strategies that induce dysfunction in the endoplasmic reticulum (ER) hold great promise for anticancer therapy, but remain unsatisfactory due to the compensatory autophagy induction after ER disruption. Moreover, as autophagy can either promote or suppress cell survival, which direction of...

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Bibliographic Details
Main Authors: Xinran Shen, Yudi Deng, Liqiang Chen, Chendong Liu, Lian Li, Yuan Huang
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202301434