Ezrin/radixin/moesin proteins and flotillins cooperate to promote uropod formation in T cells

Ezrin/radixin/moesin proteins and flotillins cooperate to promote uropod formation in T cells

T cell uropods are enriched in specific proteins including adhesion receptors such as P-selectin glycoprotein ligand-1 (PSGL-1), lipid raft-associated proteins such as flotillins and ezrin/radixin/moesin (ERM) proteins which associate with cholesterol-rich raft domains and anchor adhesion receptors...

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Bibliographic Details
Main Authors: Sibylla eMartinelli, Emily J.H. Chen, Fiona eClarke, Ruth eLyck, Sarah eAffentranger, Janis K. Burkhardt, Verena eNiggli
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Immunology
Subjects:
cell migration
Ezrin
radixin
moesin
T-lymphocyte
flotillin
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00084/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00084/full

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