<i>Cleistocalyx nervosum</i> var. <i>paniala</i> Berry Promotes Antioxidant Response and Suppresses Glutamate-Induced Cell Death via SIRT1/Nrf2 Survival Pathway in Hippocampal HT22 Neuronal Cells

<i>Cleistocalyx nervosum</i> var. <i>paniala</i> Berry Promotes Antioxidant Response and Suppresses Glutamate-Induced Cell Death via SIRT1/Nrf2 Survival Pathway in Hippocampal HT22 Neuronal Cells

Excessive glutamate neurotransmitters result in oxidative neurotoxicity, similar to neurodegeneration. An indigenous berry of Thailand, <i>Cleistocalyx nervosum</i> var. <i>paniala</i> (CNP), has been recognized for its robust antioxidants. We investigated the effects and mec...

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Bibliographic Details
Main Authors: Wanchanok Nantacharoen, Seung Joon Baek, Waluga Plaingam, Somsri Charoenkiatkul, Tewin Tencomnao, Monruedee Sukprasansap
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Molecules
Subjects:
<i>Cleistocalyx nervosum</i> var. <i>paniala</i>
glutamate
molecular mechanisms
neuroprotection
neurotoxicity
neuron injury
Online Access:https://www.mdpi.com/1420-3049/27/18/5813

Internet

https://www.mdpi.com/1420-3049/27/18/5813

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