Single-cell RNA sequencing reveals the role of cell heterogeneity in the sex difference in primary hyperparathyroidism

ObjectiveTo explore the difference in parathyroid tissue-derived cells between male and female PHPT patients.MethodsResected parathyroid tissues were collected from PHPT patients of both sexes. Single cells were isolated and sequenced for RNA expression profiles. The cell sequencing data were annota...

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Bibliographic Details
Main Authors: Shuai Lu, Xi Chen, Maoqi Gong, Shuo Chen, Jianyu Zhang, Xigong Zhang, Chengai Wu, Aimin Cui, Xieyuan Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1165890/full